Human pancreatic juice – colorless clear liquid containing 98.7% water alkaline (pH 7.5 to 8.5), which depends on the content of sodium bicarbonate. Therefore, the loss of significant amounts of juice is a violation of the acid-alkaline balance. The bulk of solids, the number of which reaches 10% is protein. The amount of protein ranges from 0.1 to 10%, depending on the content of enzymes in the juice.
The pancreatic juice contains enzymes: protease, amylase and lipase. The main proteolytic enzyme is inactive trypsinogen, which under the action of the enzyme intestinal juice – enterokinase converted to its active form – trypsin. Trypsin is composed of several proteases: actual trypsin, chymotrypsin and carboxypeptidase. Inactive chymotrypsinogen enterokinase activated and transformed into chymotrypsin. Trypsin unlike pepsin in a weakly alkaline, neutral or weakly acidic medium cleaves whole proteins and their degradation products – albumozy peptones and – to the final product, suitable for suction, – amino acids.
However, whey and egg proteins are cleaved by trypsin with difficulty and easily digested by pepsin. With 20 years of contents trypsin people decreases.
A second proteolytic enzyme – pancreatic erepsin stands in active form. Erepsin does not apply to whole proteins, but splits and albumozy peptones into amino acids.
Amylolytic enzymes of pancreatic juice: amylase, which breaks starch down disaccharides malypaza, splits ,, disaccharides to monosaccharides and lactase, which breaks lactose into monosaccharides. These enzymes are most active at a neutral reaction.
Pancreatic lipase breaks down fats juice to glycerol and fatty acids. Fatty acids with alkalis form soaps.
Almost all of lipase released into an inactive state and is activated bile acids.
The digestion of fat is increased due to its emulsification alkalis pancreatic juice and bile. Phospholipase cleaves phospholipids. In the pancreas formed protein substances which inhibit the action of proteolytic enzymes. They are expected to prevent the gland from autodigestion.