Upon standing blood to which to eliminate clotting added on anticoagulant substance gradually erythrocyte sedimentation.
The erythrocyte sedimentation rate (ESR or abbreviated) depends on the ratio of albumin and globulin in blood plasma.
The erythrocyte sedimentation rate is also a linear function of the number of red blood cells. The more red blood cell, the slower they are deposited. The volume of red blood cells has no effect on ESR, since it is relatively constant. The sooner they are glued together in the form of columns, the more quickly settle.
Under physiological conditions, ESR in males ranges from 3-9 mm, and the women – 7-12 mm per hour during the day ESR does not change. In pregnant women, it is increased by several times. Newborn first weeks of life, it is lowered, and the stump comes to standards.
ESR accelerated by inflammatory processes that dna1 has diagnostic value in clinical practice. For example, during the development of radiation sickness caused by ionizing radiation, ROE increases to 60-80 mm per hour.